3 269 patients with the clinical effects of glycated hemoglobin test analysis.docVIP

 PAGE \* MERGEFORMAT 10 3 269 patients with the clinical effects of glycated hemoglobin test analysis Of: Wang Meihua, Lu Ping Xia, Wang Fuan, Luo heart Qi, Cao Yingping [Abstract] Objective To analyze the 3 269 cases of glycated hemoglobin (HbA1c and blood glucose test results, understanding of diabetes (DM control the situation. Methods Determination of HbA1c content of samples to detect glucose oxidase electrode in the glucose content of samples . Statistics 3 269 cases were patients with impaired glucose regulation and in 1 208 patients diagnosed with DM in patients with HbA1c frequency distribution, and one of 116 cases of DM were detected in the same day, HbA1c, fasting plasma glucose and postprandial 2 h blood glucose (2 h PBG, of their correlation. Results 3 269 HbA1c results frequency distribution of P50 in the HbA1c levels of 6.6%. In 1 208 patients diagnosed with DM, the control of the ideal (HbA1c lt;6.5% for 30.6%, good control (HbA1c 6.5% 7.5% to 29.4%, poor control (HbA1cgt; = 7.5% to 40.0%. HbA1c testing the same day and 2 h PBG more closely related. Conclusion 2 h PBG test efficacy in DM is better than fasting plasma glucose. [Keywords:] Hemoglobin A, glycosylated, diabetes, blood glucose Hemoglobin (hemoglobin, Hb) chain N terminal valine amino carbonyl condensation and glucose instability Shiff’s base formation, followed by Amadori translocation, molecular rearrangement to form a stable olamine, the glycated hemoglobin A1c (hemoglobin A1c, HbA1c). Hb hexose occurred with the slow formation of non-enzymatic reaction of a compound known as glycated hemoglobin (glycated hemoglobin, GHb) [1]. GHb outside the red blood cell production rate and has been proportional to the concentration of sugar, HbA1c was studied GHb The most widely used. Hb in blood glucose and the combination of the process until the red blood cell death exist, so new in vivo aging of red blood cells than red blood HbA1c levels of about 1.5 times higher. Each red bl