37 treatment of Alzheimers Disease Research Progress.docVIP

 PAGE \* MERGEFORMAT 17 37 treatment of Alzheimer’s Disease Research Progress [Abstract] Objective To review the 37 in the treatment of Alzheimer’s disease (Alzheimer’s disease, AD) research progress. Method of access to relevant literature at home and abroad, and its analysis, summarized and concluded. Results 37 with improved memory and cognitive function, inhibiting β -amyloid damage, anti-oxidation and brain protection. Conclusion 37 can be used for the treatment of Alzheimer’s disease. [Keywords:] Alzheimer’s disease; 37; 37 total saponins Research Progress on the Treatment to Alzheimer’s Disease with Panax Notoginseng Abstract: Alzheimer’s disease (AD) is one kind of neurodegeneration disorders, which is a main cause to the dementia. Panax notoginseng, one traditional Chinese medicine, which is able to activate blood transforming stasis and enrich blood, has been proved to be effective in AD treatment in clinic and at laboratory.In this article, we summarized recent alien and native papers and reviewed the mechanisms of Parax notoginseng in AD treatment including improving ability of memory and cognition, inhibiting the toxicity of β -amyloid peptide, anti-oxidation, protecting the brain and so on. Keywords:: Alzheimer’s disease; Panax notoginseng; Panax notoginseng saponins AD, mainly in the elderly population, the clinical characteristics of memory loss, progressive cognitive dysfunction and emotional disorders. The pathological features are mainly β -amyloid protein (Amyloid β , Aβ ) consisting of senile plaques and by Tau protein phosphorylation caused by abnormal neurofibrillary tangles, and by β -amyloid protein and abnormal phosphorylation of Tau protein, caused by nerve cells from oxidative stress, inflammatory response and apoptosis such as injury. The current treatment of AD drugs is mainly acetylcholinesterase inhibitors, and the lack of drugs for the treatment of pathological changes. Modern Traditional Chinese Medicine study concluded