4 things Capsule Water Extraction Process Optimization.docVIP

 PAGE \* MERGEFORMAT 8 4 things Capsule Water Extraction Process Optimization [Abstract] Objective To determine the four material capsules optimum water extraction. Methods The orthogonal test method, in order to extract the gains volume and the amount of paeoniflorin extract optimal extraction as an indicator. The results to extract two times, each time with 10 times the amount of water boiling 2 h as the best extraction process. Conclusion preferred process is stable and feasible. [Keywords:] 4 complex capsules; extracts; peony; paeoniflorin; extraction process; orthogonal design 4 things capsule is Rehmannia glutinosa, Angelica, white peony, Chuanxiong four Chinese herbal medicines, has a Tiaojing nourishing functions for the battalion of blood weakness, irregular menstruation. As early as in the ‘Sin burdened with injuries Dipsacus secret’ in the square will be called ‘the blood of the special party, menstruation the good agent’. Fang TGP bitter, sour, sexual cool, entry 2 by the liver and spleen, there are nourishing Rougan, ease in pain, grabbing Yin received the efficacy of Khan [1  3]. Reference to the traditional extraction process ‘four things mixture’ of the extraction methods, preparation is more cumbersome and, therefore, we in the light of the original process based on the extraction of water by adding water and boiling time for multiple orthogonal experimental design in order to dry weight and cream comprehensive consideration of paeoniflorin as an indicator to select the prescription of optimal extraction process, the report is as follows. An experimental material Instrument: LC  10AD high-performance liquid chromatograph, SPD  10A (SHIMADZU) UV-visible spectrophotometric detector, LC  10AD (SHIMADZU) LIOUID CHROMATOGRAPH, HW  2000 chromatography workstation (SHIMADZU); HT  230A column temperature box (COLUMN HEATER ); C  21 chromatography data acquisition unit; Shimadzu UV  2401 UV scanner; ELECTRONIC BABANCE (AY220, SHIM