90 cases of patients with idiopathic male infertility Cytogenetic chromosome analysis of variance.docVIP

 PAGE \* MERGEFORMAT 10 90 cases of patients with idiopathic male infertility Cytogenetic chromosome analysis of variance Of: the party Peng Liang Jie Chen Yintao Huozheng Hao Wang Jiao Haiyan Zhao Zhong Huijun Wei Lu [Abstract] Objective To investigate the nature of the relationship between chromosome abnormalities and male infertility. Blood lymphocyte culture conventional method to prepare chromosome samples, G-banding, karyotype analysis microscope, if necessary, the line C-banding assistant examination, karyotype analysis by International naming system of human cytogenetics (ISCN) for. results in the selected 90 cases of male infertility, including eight kinds of chromosomal aberrations CPC abnormal karyotype. the number of abnormalities in 36 cases (40.00%), structural abnormalities in 53 cases (58.89%) The number of structural abnormalities of one case of combined anomalies (1.11%), mainly for low sperm or no sperm syndrome. conclusions of human sex chromosomal abnormality is one of the main factors leading to male infertility. [Keywords:] male infertility; sex chromosome abnormalities; cell genetics; karyotype analysis Male infertility is a complex disease, genetic factors involved in many. It is reported that worldwide about 15% to 20% of infertile couples of reproductive age, of which 40% of the reasons for male infertility. Karyotype abnormalities the main cause of male infertility, in which the number of sex chromosome abnormalities or changes in the structure will cause abnormal development of male sexual or reproductive abnormalities and other genetic effects. We selected 90 cases of sex chromosome karyotype of male infertility, and the karyotype explore the relationship between the disease. 1 Materials and Methods 1.1 The World Health Organization data (WHO) definition of infertility is one year or more couples living together, not use any contraceptive measures, due to male factor infertility caused by the woman. We chose Ma