About BYHWD cerebral infarct volume after ischemia and Pathological Changes.docVIP

 PAGE \* MERGEFORMAT 10 About BYHWD cerebral infarct volume after ischemia and Pathological Changes [Abstract] Objective BYHWD cerebral infarct volume after ischemia and pathological changes. Methods suture method using rat model of focal cerebral ischemia. The healthy male SD rats randomly divided into sham operation group, model group, BYHWD group. The rats were sacrificed underwent TTC and HE staining to determine infarct volume and observe the pathological changes. Results BHD ischemic rats pathological changes in brain tissue compared with model group, infarct volume was significantly smaller than the model group (P lt;0.01). conclusions can BYHWD after cerebral ischemia and reperfusion reduced infarct volume, reduce the pathological changes of the brain missing blood reperfusion injury in rats. Keywords:] BHD, cerebral ischemia, cerebral infarct volume Abstract: Objective To investigate the influence of Buyanghuanwu (BYHW) Decoction on cerebral infarct volume and pathological changes after cerebral ischemia and reperfusion. Methods The model of focal cerebral ischemia and reperfusion was made by thread embolism method. Healthy male SD rats were divided randomly into sham-operated group, model group and BYHW Decoction group. Infarct volume was detected by triphenyltetrazolium chloride (TTC) staining and pathological changes were observed microscopically in HE stained sections. Results In BYHW Decoction group, infarct volume was significantly smaller than that in model group (P lt;0.01), pathological changes were better than those in model group. Conclusion BYNW Decoction could decrease the cerebral infarct volume and alleviate the pathological changes after cerebral ischemia and reperfusion. It possesses protective effect against cerebral ischemia-reperfusion injury. Keywords:: Buyanghuanwu Decoction, cerebral ischemia, pathology, cerebral infarct volume in ischemic cerebrovascular disease is a common disease with high incidence and high morbidity