Airway remodeling and bronchial asthma and Overview.docVIP

 PAGE \* MERGEFORMAT 15 Airway remodeling and bronchial asthma and Overview [Abstract] Objective media aspects of airway remodeling and airway remodeling of bronchial asthma, the development of relations. Method to retrieve the China Academic Journal (CNKI), Chongqing VIP Database Technology Journal (VIP) and Wanfang database, which will be on bronchial asthma, airway remodeling and experimental studies the relationship between literature, Meta analysis in accordance with international standards lt; gt; 18 entries in the extraction and related requirements of the relevant literature met the inclusion criteria data for airway remodeling and bronchial asthma and evaluation. Results A total to 59 with bronchial asthma airway remodeling and experimental study of the relationship between literature, of which met the inclusion criteria and does not meet the exclusion criteria, 25 articles were pooled analysis; results show that smooth muscle cells, myofibroblasts, matrix metalloproteinase 9 (MMP 9) and their inhibitors (TIMP 1), interleukin-neutrophil etc. and asthma attacks, asthma-related media rationale for changing the airway remodeling in asthma have greater role in the formation. Conclusion airway remodeling of bronchial asthma as one of the important pathological changes, the situation should be the evaluation of asthma control is an important observation indicators. [Keywords:] Asthma; airway remodeling; airway disease / experiment; document analysis Bronchial asthma (the asthma) is a combination of cells, including airway inflammatory cells and structural cells and cellular components involved in chronic inflammatory airway diseases [1], is the most common chronic diseases. At the same time, a large number of Experimental studies also show that asthma not only in airway inflammation, but also the changes of airway structure that airway remodeling [2]. airway remodeling and regulation of independent genetic pathway, but on the molecular mechanisms