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Allograft reconstruction of large segmental bone missing limbs
Of: Wang Song, seeding Wing Kun, Zhang Peiqin, Jia-Hua Tan, Wuliang Jun, Guo Yaxiong
[Abstract] [Objective] To investigate a large area of bone allograft for the treatment of bone loss. [Methods] Bone loss has been for centuries the repair of bone surgery is an important issue journalists continue to study. Although autogenous bone grafts are generally recognized However, large areas of bone loss but can not get enough autogenous bone, and human allograft materials and autologous bone is very similar, it has a three-dimensional pore structure of human bones, better materials, and biological characteristics, and in the bone conduction and bone induction ability are more advantages. but how large bone loss with bone allograft, reducing the host inflammatory response and graft immune rejection, complete bone induction and bone conduction, bone grafts were gradually replaced with autologous bone process, since May 2000 -2004 admitted in July a total of 3 cases of large segment of the missing limbs of patients, different segments, the lengths of 6 ~ 12 cm of the allograft bone transplant, at the same time effective treatment of fixed and anti-immune rejection. [Results] were successfully transplanted, each patient followed up for 2 years, the longest follow up of 3 years, patients return visit X-ray showed bone graft autogenous bone gradually been replaced by functional recovery of limb normal. [Conclusion] to effectively deal with fixed-and anti-large segment of immune rejection of allogeneic bone transplantation, can physically rebuild large bone defects.
[Keywords:] large bone loss, allogeneic bone graft, reconstruction
For severe trauma, infection of the tumor into the fracture nonunion caused caused massive bone loss, how to fix in order to restore the continuity and function of bone is still the main problem facing the orthopedic. The reconstruction of massive bo
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