Alzheimers disease in Chinese population meta-analysis of risk factors.docVIP

 PAGE \* MERGEFORMAT 15 Alzheimer’s disease in Chinese population meta-analysis of risk factors [Abstract] Objective To investigate the Chinese population of senile dementia (AD) that the main risk factors for the prevention decisions. Methods January 1980 to November 2008 at home and abroad published the independent risk factors on the AD case-control study and used RevMan software to the comprehensive and quantitative meta-literature, the use of chi-square value and p value of analysis of the results of statistical heterogeneity between. The results included in this meta-analysis of the literature a total of 11 cumulative cases of 1 420 patients in the control 2 901 cases. AD risk factors combined relative risk (OR) values and 95% confidence interval (95% CI) were: family history of dementia (OR = 2.62,95% CI (1.69 ~ 4.07)), widowed (OR = 1.53,95% CI (1.21 ~ 1.93), drinking (OR = 0.87,95% CI (0.68 ~ 1.12), smoking (OR = 0.80,95% CI (0.67 ~ 0.95). Conclusion Family history of dementia and widowed people in China are currently affecting the risk factors of AD. [Keywords:] Alzheimer’s disease, risk factors, meta-analysis In people over the age of 60, Alzheimer’s disease (AD) prevalence rate of about 1.6% (1), and with the aging of the population has become more evident, AD as the most common type of dementia, will will become an important medical and social issues (2). but has yet to clarify its specific etiology and pathogenesis. meta-analysis has the advantage to increase the sample size by increasing the reliability of conclusions, to solve the inconsistency of the results. This By 1980 China 2008 published on risk factors for AD in Chinese population case-control study conducted meta-analysis to analyze and explore the domestic risk factor for AD group for future prevention and control of the disease provide a reference. 1 Materials and methods 1.1 Source Journal of Chinese science and technology through computer search text databases, full