Bone Tissue Engineering Research and Prospect.docVIP

 PAGE \* MERGEFORMAT 17 Bone Tissue Engineering Research and Prospect [Keywords:] bone tissue engineering The basic meaning of tissue engineering is used alone or in the cells, cytokines and biological materials used in composite Yihou living tissue regeneration in vivo and in vitro tissue construct. Medical organizations as an important part of engineering, bone tissue engineering is for nonunion bone defects, especially large bone defects (diametergt; 5 mm) of the filling and healing of this clinical problem, study effective therapeutic approach. Its idea is in the body of nonunion or bone defect bone implant containing a high vector system of seed cells, bone induction and bone conduction to provide the best environment in the local bone directly into the bone and complete the healing process. the last century, people 60 to 70 years of bone growth factors - bone morphogenetic protein (bone morphogenetic proteins, BMPs) in-depth understanding and opened up a new era in bone tissue engineering. In the early bone tissue engineering, it is mainly to focus on the cultivation of seed cells, searching for seed cells to survive and design of the carrier above the vector space structure. In recent years The study confirmed the success of bone regeneration is one of the determinants of graft revascularization, the vascular tissue engineering of bone regeneration in its own survival and the healing of the host bed play an important role. for bone tissue engineering , the rapid vascularization of bone cell function can provide adequate nutrition activities, decided the amount of bone formation, and only developed into vascularized autologous bone to bone, which play a long-lasting in vivo physiological functions. Therefore, improving the organization engineered bone blood supply, build capillaries of the tissue engineering of bone has become a research hotspot. A source of seed cells for bone formation and selection Seed cells for bone tissue engineering is