Chinese medicine in peritoneal dialysis-related prevention and treatment of peritoneal fibrosis.docVIP

 PAGE \* MERGEFORMAT 13 Chinese medicine in peritoneal dialysis-related prevention and treatment of peritoneal fibrosis Abstract peritoneal dialysis (PD) is the treatment of end-stage renal disease, one of the more effective ways, but because of the currently used peritoneal dialysis fluid bio-incompatibility could easily cause the destruction of peritoneal structure and function, expressed in peritoneal mesothelial cells injury, necrosis, cell regeneration and repair barriers, followed by fibrous tissue proliferation, eventually leading to peritoneal fibrosis, which is a major long-term peritoneal dialysis complications in peritoneal dialysis patients is the main reason for the final withdrawal from peritoneal dialysis treatment. Modern pharmacological experiments show that many Chinese medicines have anti-fibrosis, some traditional Chinese medicine used in peritoneal dialysis patients, can prevent or delay the occurrence and development of peritoneal fibrosis. Keywords: peritoneal dialysis peritoneal fibrosis in kidney disease medicine In recent years, Chinese medicine used in peritoneal dialysis in preventing peritoneal fibrosis and improve the effectiveness of dialysis has a positive effect. In this paper, Chinese medicine in prevention and treatment of peritoneal fibrosis in an overview of the role and mechanisms [1]. 1 and peritoneal fibrosis-related cells Has now confirmed that peritoneal mesothelial cells (HPMC), macrophages (Mφ) involved in peritonitis, peritoneal fibrosis, the main cells in the process. HPMC is a primary peritoneal surface cell layer, peritoneal dialysis, HPMC not only as a biological barrier for ultrafiltration and solute transport, but also has important metabolic and secretory functions in the maintenance of a stable environment within the peritoneum plays a key role [2]. Peritoneal Mφ is the abdominal cavity against microbial invasion of the main cell population, peritoneal Mφ and HPMC 1 to