Chuanxiong HPLC fingerprint of particles.docVIP

 PAGE \* MERGEFORMAT 11 Chuanxiong HPLC fingerprint of particles Authors: HAN, HUANG Yuan Li, Yang, Xie Xiuqiong [Abstract] Objective To establish a high-performance liquid chromatography Chuanxiong particles (HPLC) fingerprints. Methods Kromasil KR-100-5 C18 column, 0.5% phosphoric acid solution and methanol gradient elution, flow rate of 1.0 ml / min, detection wavelength was 240 nm, column temperature of 20 ℃ . The results obtained separation and repeatability better than those of HPLC fingerprint Chuanxiong particles, marking a total of 11 peaks in 10 groups Chuanxiong granules HPLC fingerprinting similarity evaluation, and with Chuanxiong Pieces comparative study of HPLC fingerprint. Conclusion Chuanxiong granules HPLC fingerprint of the establishment of a basis for quality control. [Keywords:] Chuanxiong granules; high-performance liquid chromatography; fingerprint Abstract: ObjectiveTo establish the analytical method for the fingerprint of Chuanxiong Dispensing Granules by HPLC. MethodsSeparation was performed on a Kromasil KR-100-5 C18 column, with mobile phase consisting of 0.5% phosphoric acid-water and methanol and with gradient elution at the flow rate of 1.0 ml / min. The UV detection wavelength was 240 nm, column temperature was 20 ℃ . ResultsAn HPLC fingerprint for Chuanxiong Dispensing Granules was established Both fidelity and reparability were good. It had 11 common peaks. ConclusionAccording to the foundation of HPLC fingerprint, we can control the quality of Chuanxiong Dispensing Granules. Keywords:: Chuanxiong Dispensing Granules; HPLC; Fingerprint Chuanxiong particles as Chuanxiong Umbelliferae Ligusticum chuanxiong Hort. Rhizome dry processed granules made of mainly contains alkaloids, organic acids and volatile oil components. Function Qi and blood circulation, expelling wind analgesics for the treatment of irregular menstruation, amenorrhea dysmenorrhea, Zhengjia abdominal pain, Xiong Xie tingling or flutter swelling, pain, head