Controlled ovarian stimulation after injection of HCG causes of the decline of estradiol levels.docVIP

 PAGE \* MERGEFORMAT 16 Controlled ovarian stimulation after injection of HCG causes of the decline of estradiol levels [Abstract] [Objective] controlled ovarian hyperstimulation (COH) after injection of HCG during the estradiol (E2), and other changes in hormone concentrations and to analyze the impact on pregnancy outcome. [Method] prospective study of 74 routine COH infertility patients, peripheral venous blood test taken the basis of sex hormone levels in patients, starting at follicle stimulating hormone (FSH), luteinizing hormone (LH) and E2 and the HCG injection day, ovum (OPU) at transplant (ET) Day LH, E2 and progesterone (P) concentrations. pregnancy is divided into groups according to pregnancy outcome (n = 28) and non-pregnant group (n = 46). [Results] 74 patients with HCG injection day, OPU day and day of the E2 ET [(2 380 + - 1 177 vs. 839 + - 446 vs. 1 199 + - 634) pg / mL, P lt;0.01], P [(0.50 + - 0.29 vs. 7 + - 4 vs. 84 + - 48 ) ng / mL, P lt;0.01] concentrations significantly. HCG day and the number of oocytes (r = 0.602, P lt;0.01), OPU day (r = 0.545, P lt;0.01) E2 were positively correlated. pregnant group and non-pregnant group sex hormone levels based on age ?p ?p ?p the number of oocytes fertilized and the number of number of transferred embryos ?p HCG injection at ?p OPU and ET on day LH ?p E2 and P, no significant difference (Pgt; 0.05). HCG on pregnancy group, OPU, and ET on the date of E2 [(2 400 + - 1 116 vs. 909 + - 492 vs. 1 263 + - 662) pg / mL, P lt;0.01], P [(0.5 + - 0.4 vs. 6 + - 3 vs. 79 + - 38) ng / mL, P lt;0.01] were significant differences in concentration. HCG day of non-pregnant group, OPU, and ET on the date of E2 [(2 369 + - 1 225 vs. 797 + - 466 vs. 1 161 + - 621) pg / mL, P lt;0.01], P [(0.52 + - 0.28 vs 7 + - 4 vs 87 + - 51) ng / mL, P lt;0.01] of difference between the concentration of the same statistical significance. [Conclusion] COH in, E2 concentrations decreased significantly after HCG injection, the day