Danshen injection in the treatment of hypoxic ischemic encephalopathy Efficacy.docVIP

 PAGE \* MERGEFORMAT 5 Danshen injection in the treatment of hypoxic ischemic encephalopathy Efficacy [Abstract] Objective To observe the compound Danshen injection treatment of neonatal hypoxic-ischemic encephalopathy (HIE) of clinical efficacy. Methods 40 patients were randomly divided into treatment group and control group, 20 cases of 20 patients, the treatment group were based added with compound Danshen injection 1 / d, for 7 to 10 days. Results The main clinical manifestations in children treated group the improvement was better than control group. Conclusion widely used compound Danshen injection in the treatment of HIE can be significantly improved Brain cells and neural regulation of the use of oxygen. [Keywords:] hypoxic ischemic encephalopathy; Danshen; clinical efficacy; neural regulation Hypoxic ischemic encephalopathy (HIE) is the child of perinatal brain damage caused by the main reason leading to one common cause of neurological disability. Often clear in the clinical history or birth asphyxia had abnormal neurological symptoms within 12h . domestic and international research confirms oxygen free radicals (OFR) release in the pathogenesis of HIE played a major role. now with the deepening of medicinal Salvia, Salvia solution components in the chemistry, pharmacology, there is new discovery, its scope of application expanding, as oxygen free radical scavenger effect in the treatment of HIE in the original treatment based on the use injection, to obtain a more satisfactory clinical outcome. 1 Materials and Methods 1.1 The choice of cases selected in February 2008 -2010 hospitalized in February were 40 cases of HIE children meet the diagnostic criteria of neonatal HIE and in accordance with sub-clinical manifestations and CT changes in light, moderate and severe. The treatment group 20 cases, light 10 cases, in 7 patients, re-3; including 12 males and 8 females; weight lt;2500g 2 , 2500 ~ 4000g 16 ,gt; 4000g 2 ; Apgar score 0 to 3 i