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Detection of multiple tumor markers in the diagnosis of malignant tumors of
PAGE \* MERGEFORMAT 9
Detection of multiple tumor markers in the diagnosis of malignant tumors of
[Abstract] Objective To investigate alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3) and ferritin (Ft) and other tumor markers of primary liver cancer, lung cancer and colorectal cancer diagnosis. Methods 80 cases of primary liver cancer were detected, 123 patients with lung cancer and 66 cases of colorectal cancer. The results of 5 individual determination of tumor markers positive rate was 12.6% -77.5%, positive rate of combined determination of 80.3% ~ 91.3%, the difference was significant (P lt;0.05). in the selection of indicators, the liver preferred AFP, Ft, and CA199, cancer preferred CEA, Ft , colorectal cancer preferred CEA, CA19-9. Conclusion Combined detection can improve the positive rate, can also be targeted to select tumor markers.
[Keywords:] AFP CEA carbohydrate antigen 19-9 ferritin carbohydrate antigen 15-3 Detection of various tumor markers in cancer diagnosis, prognosis, efficacy and recurrence monitoring, etc., has been attached. 269 cases of cancer of the determination of alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), sugar antigen 15-3 (CA15-3), carbohydrate antigen 19-9 (CA19-9), ferritin (Ft) and other 5 kinds of tumor markers, and analysis of their primary liver cancer, lung cancer, colorectal cancer diagnosis.
1 Materials and methods 1.1 specimens from 80 patients with primary liver cancer, 123 cases of lung cancer and 66 cases of colorectal cancer patients were a total of 269 hospital cancer clinic or hospital patients, were confirmed by surgery or pathology cytology. Male 162, female 107 patients, aged 29 to 78 years, mean 55 years.
1.2 Experimental Methods patients were fasting morning blood sample, 2h the separation of serum, -20 kept under test. AFP, CEA Ft, CA19-9, CA15-3 were imported original Abbott reagents
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