Drug-induced rash clinical analysis of 104 cases of hospitalized children.docVIP

 PAGE \* MERGEFORMAT 3 Drug-induced rash clinical analysis of 104 cases of hospitalized children [Keywords:] rash Drug-induced rash of allergic diseases among children is an important part of children in order to explore the age distribution of drug-induced rash, skin rash type, the characteristics of allergenic drugs and treatment, this article in our hospital 104 cases of drug-induced rash clinical data of hospitalized children analysis, are reported as follows: 1 Data and methods 1.1 General Information In this group from January 2001 to December 2006 hospitalized patients, a total of 104 cases, male 65 cases, female 39 cases. Out-patient directly to hospital for treatment of drug-induced rash of income of 38 cases, more than 66 cases were in the treatment of other diseases due to skin rash and the diagnosis process. All patients had varying degrees of itching, 52 cases of children with fever, of which 10 cases of severe drug-induced rash were fever. 1.2 Diagnosis Diagnostics are based on the history of rash medication before a clear history of more than the initial 7 ~ 10 d after administration rash, if previously subject to the same or similar medications may be hours or 1 ~ 2 d rash. Clinical to exclude infection or rashes caused by other factors, then the diagnosis of drug-induced rash. Rash type identified by Zhao [1] proposed a sub-type methods, sensitizing drugs based on ‘A New Drug learning’ category. 1.3 Treatment Suspended immediately upon diagnosis of a sensitizing drugs, in addition to selection of a newborn things are oral antihistamines. All patients had to be of calcium gluconate and vitamin C treatment. 18 cases of light-medium-sized to be drug-induced rash and dexamethasone 0.3 ~ 0.5 mg / (kg * d) treatment, 23 cases to be of methylprednisolone 1 ~ 2 mg / (kg * d) treatment. Severe drug-induced rash one diagnosed in sufficient quantities for immediate use of adrenal corticosteroids, seven cases of methylprednisolone to be 3 ~ 5