Effect of octreotide on human hepatoma cell line MHCC97H of.docVIP

 PAGE \* MERGEFORMAT 2 Effect of octreotide on human hepatoma cell line MHCC97H of Author: Liu Light, Song Tao, Sun Hao, Shi Lei, Zhang Mei [Abstract] Objective To investigate the effects of octreotide on human high-metastatic potential of hepatocellular carcinoma cell line MHCC97  H effect and its mechanism. Method of octreotide in vitro on the growth of logarithmic phase high-metastatic potential of human hepatocellular carcinoma cell line MHCC97  H, observe the growth curve of the change; application of MTT colorimetric analysis method, cell growth inhibition; changes in cell morphology was observed under transmission electron microscope. The results of octreotide in the 0.2mg / L mass concentration intervention MHCC97  H cells in vitro so that the growth was inhibited; observed under transmission electron microscopy showed morphological changes of apoptosis; in 0.05-0.8mg / L concentration range of dose-dependent inhibition in human high-metastatic potential of hepatocellular carcinoma cell line MHCC97  H proliferation (P