Endophytic actinomycetes and antibacterial activity of host plants and their relationship.docVIP

 PAGE \* MERGEFORMAT 7 Endophytic actinomycetes and antibacterial activity of host plants and their relationship Author: ZHONG Li Tian Xin-Li Zhou Min Wang Tao, Cheng Akika FAN Yun-Zhong-Jun Qin Zhenhua [Abstract] From the 68 kinds of Chinese herbal medicine plant isolated 560 strains of endophytic actinomycetes, of which 84 (about 15%) have antibacterial activity against Staphylococcus aureus, 36 (about 6%), Candida albicans has antimicrobial activity, suggesting that the endogenous Chinese Herbal Medicine actinomycetes could be a source of antibacterial drugs. Detection of the nine kinds of Chinese herbal plants on the water or ethanol extracts of the antibacterial activity against Staphylococcus aureus and found that strains of endophytic actinomycetes antibacterial activity of host plants with no obvious correlation. [Keywords:] herbal plants; Endophytic Actinomycetes; antimicrobial activity ABSTRACT This paper reports that total 84 or 36 out of the tested 560 endophytic actinomycetes strains from 68 Chinese medicinal herbs, showed inhibition activity against Staphylococcus aureus or Candida albicans, respectively, suggesting a potential source for novel antibiotics. Further investigation by using water or ethanol extracts of the nine herbs against Staphylococcus aureus, indicated no apparent relationships on inhibition of the pathogen between herbs and their endophytic actinomycetes. KEY WORDS Chinese medicinal herbs; Endophytic actinomycetes; Inhibition activity Currently found in actinomycetes (mainly from soil) produces antibiotics and more than 10,000 kinds of physiologically active substances, accounting for microbial agents have been found about 2 / 3 [1]. In recent years, separated from the original habitat actinomycetes and finding new antibiotics has gradually been taken seriously, such as isolated from plants within the organization of its endophytic actinomycetes and finding new antibiotics [2]. Chinese herbal medicine in China has abundan