Expression of VEGF and MVD in the early diagnosis of peripheral lung cancer imaging in the value and correlation analysis.docVIP

 PAGE \* MERGEFORMAT 12 Expression of VEGF and MVD in the early diagnosis of peripheral lung cancer imaging in the value and correlation analysis Study: Zhen Zhen Wu Renhua Zheng Zheng Yu Chang Li Xiaolan Yang Kang Dong Qiongxiong [Abstract] Objective To investigate endothelial growth factor (VEGF and microvessel density (MVD expression in the early diagnosis of peripheral lung imaging in the application. Methods 68 patients with pathologically confirmed peripheral lung cancer (adenocarcinoma 32, squamous cell carcinoma 30 cases, six cases of small cell carcinoma by immunohistochemistry using LDP to detect tumor samples the expression of VEGF, MVD, and its relationship with the relationship between the imaging findings. Results VEGF and MVD was positively correlated (r = 0.691, p lt;0.01, VEGF and MVD expression in peripheral lung cancer histological type (pgt; 0.05, and tumor size, lobulation, spinous process, pleural indentation, vascular convergence sign, mediastinal lymph node metastasis and pleural effusion imaging findings were related (p lt;0.05, but has nothing to do with spiculation (pgt; 0.05). Conclusion peripheral lung imaging findings with the expression of VEGF and MVD are closely related, when the tumor diameter greater than 3cm, there lobulation, spine like processes, pleural indentation, vascular convergence sign, mediastinal lymph node metastasis and other signs of pleural effusion, suggesting that the tumor may have a higher degree of malignancy. [Keywords:] lung X-ray computed immunohistochemistry [Abstract] Objective To investigate endothelial growth factor (VEGF) and microvessel density (MVD) in the early expression of peripheral lung imaging diagnosis. Methods 68 cases confirmed by surgery and pathology of peripheral lung cancer (32 cases of adenocarcinoma, 30 cases of squamous cell carcinoma and small cell carcinoma 6) LDP used immunohistochemistry to detect tumor samples MVD and VEGF expression and analysis of its operation