Extracorporeal shock wave energy and study the relationship between rabbit kidney damage.docVIP

 PAGE \* MERGEFORMAT 11 Extracorporeal shock wave energy and study the relationship between rabbit kidney damage [Abstract] Objective To establish a rabbit model of extracorporeal shock wave injuries to investigate the impact of different voltage and frequency of impact damage to the kidneys. Methods 30 rabbits of different extracorporeal shock wave (14 KV 1 000 times, 14 KV 2 000 times , 14 KV 3 000 times, 12 KV 2 000 times and 10 KV 2 000 times of injury, determination of urinary albumin, N-acetyl--D glucosaminidase, -glutamyl transferase and IgG level, and pathological observation. Results of extracorporeal shock wave urinary albumin after injury, N-acetyl--D-glucosaminidase and -glutamyl transferase levels increased, while no significant changes in IgG, With the increase in the number and impact of the impact of higher voltage, urinary albumin, N-acetyl--D-glucosaminidase and -glutamyl transferase enzyme levels, pathological observation showed different degrees of renal injury. Conclusions Extracorporeal shock wave energy increase can aggravate kidney damage, effects of proposed gravel does not affect the premise should be to minimize the number of impulse voltage and reduce the impact. [Keywords:] extracorporeal shock wave lithotripsy of renal injury in voltage albumin Abstract: Objective To study the relationship between renal injury severity and discharge voltage, shock times in renal injury models of rabbits after ESWL. Methods 30 white rabbits were randomly divided into five groups, and each group was disposed by different ernergy (group A: 1 000 shocks at 14 KV, group B: 2 000 shocks at 14 KV, group C: 3 000 shocks at 14 KV, group D: 2 000 shocks at 12 KV, group E: 2 000 shocks at 10 KV). The urinary NAG , -GT, ALB, IgG and Cr were measured 24 hours before and after ESWL. The histological changes of Kidneys in rabbits was observed 24 hours after ESWL. Results The urinary NAG / Cr, -GT/Cr, ALB / Cr increased significantly after ESWL, but