Extract of red blankets experimental study on antitumor.docVIP

 PAGE \* MERGEFORMAT 9 Extract of red blankets experimental study on antitumor [Abstract] Objective: To study the extracts of red blankets cancer. METHODS: MTT assay with extracts of red blankets 13 tumor cell lines in vitro growth inhibition. Results: The extract of red blankets to the tumor cell lines tested growth in vitro were significantly inhibited, in which cells of acute T cell leukemia Jurkat, human renal cell carcinoma OS RC 2, people with chronic medullary leukemia K562, human lung cancer cells A549 and human breast cancer cells MDA MB 435s of stronger, half inhibitory concentration (IC50) were 9.25 + + -3.74,11.21 -2.40,10.90 -3.68,10.75 + + -3.07 and 12.66 + -1.19 μg · ml-1, followed by human esophageal cancer cell Eca 109 human pancreatic cancer cells PANC 1, human melanoma cell A375, human hepatoma cell QGY 7703 and human gastric cancer cell SGC 7901, half inhibitory concentration (IC50) were 14.36 + -2.26,15.36 + -6.73,15.48 + -1.98, 17.21 + -10.32 and 19.01 + -5.95 μg · ml-1. Conclusion: The extract of red blankets with broad-spectrum anti-tumor effect. [Keywords:] red blankets extract; MTT; spectrum; IC50 Red Felt (Ardisia mamillata), also known as Guang Jiang, tiger tongue, orang cursory tires, red carpet mamillata, is Myrsinaceae plants, is a widely distributed in southern China’s herb with Qingre wet, the efficacy of blood and blood stasis, commonly used in the treatment of dysentery, hepatitis, cholecystitis, rheumatism, bruises, injured workers, hemoptysis, hematemesis, women, dysmenorrhea, metrorrhagia, infantile malnutrition product, furuncle carbuncle swollen pain [1]. the leaves and the stem cortex and pith with secretory tissue that contains red-brown resin material, rock cabbage lactones, volatile oil, flavonoids, glycosides, tannins and quinone [2], it has a wide range of biological activities , to examine extracts of red felt anti-tumor effect, we used MTT assay extracts of red blankets to 13 kinds of tumor cell lines in