Extraction of berberine.docVIP

 PAGE \* MERGEFORMAT 24 Extraction of berberine [Abstract] berberine, as commonly used in clinical medicine ingredients are widely used for improving the extraction yield of berberine, berberine extraction process in recent years many researches. In this paper, an overview of berberine extraction technology in recent years are reviewed. [Keywords:] berberine berberine extraction orthogonal Huangbai 3-pin Abstract: Being the common medicine, berberine has extensive applications in clinical pharmacy.There have been many studies to improve the yielding rate of berberine in recent years.The article sums up studies on the extracting technology of berberine. Keywords:: Berberine; Extraction technology; Rhizoma Coptidis; Phellodendron amurense Rupr; Berberis; Orthogonal test Berberine also known as berberine, widely distributed in the plant kingdom, about 4 Section 10 species have been found in the existence of berberine. Berberine is a yellow needle-like crystals, manifested as quaternary ammonium type, alcohol-type three kinds of tautomers, of which the most stable quaternary ammonium base type. Berberine can be slowly dissolved in cold water (1:20) or cold ethanol (1:100), in hot water or hot ethanol, the solubility of relatively large, difficult to dissolve in alcohol, chloroform or benzene, the solubility of salts are more small, sulfate solubility in water is about 1:30, hydrochloric acid salt, slightly soluble in cold water. Berberine from the three needles, Coptis, Phellodendron and other plant extracts. As Coptis slow growth, higher prices and fewer Huangbai sources are mainly used in China as a three-pin extraction of raw materials. Berberine is a common clinical broad-spectrum antimicrobial drugs, mainly used for bacillary dysentery, gastroenteritis, bacterial infections such as carbuncle swollen. Modern studies have shown that berberine has anti-tumor, anti-arrhythmia, blood pressure, blood sugar lowering effect, there are more and more widely in cli