Extraction method of Chinese medicine Sophora comparison and optimization of process conditions.docVIP

 PAGE \* MERGEFORMAT 7 Extraction method of Chinese medicine Sophora comparison and optimization of process conditions [Keywords:] traditional Chinese medicine Abstract: Objective To optimize the extraction of Sophora flavescens in Oxymatrine process. Methods of multi-extraction process. Such as the decoction method, filtration method, ethanol reflux method, orthogonal design of the extraction of matrine screening process, using high performance liquid chromatography of the ingredients, as the evaluation index. The optimum results for the filtration assay. Optimum conditions are: plus 10 times the amount of 65% ethanol-soaked 24 h after the infiltration, flow rate of 5 ml / min, oxymatrine content and extraction rate were high. Conclusion The optimized process is simple and good stability. Keywords: Sophora flavescens; oxymatrine; Orthogonal design; Extraction Process Study on Different Extraction Process of Oxymatrine in Radix Sophorae Flavescentis and Optimization Abstract: ObjectiveTo optimize the extraction process of oxymatrine in Radix Sophorae Flavescentis.MethodsSeveral extraction processes were used, such as decocting method, the refluxing method, leakaging method.The optimum extraction was investigated by the orthogonal design, oxymatrine was determined by HPLC.ResultsThe optimum extraction conditions were 10 fold of 65% ethanol, marinating 24 hours and the velocity of flow was 5ml/min.The content of oxymatrine and extraction and extraction rate were fairly high.ConclusionThis optimized method is simple, stable and efficient. Keywords:: Radix Sophorae Flavescentis; Oxymatrine; Orthogonal design; Extraction process Chinese medicine is a leguminous plant Sophora Sophora Sophora flavescens Ait dry root, there is heat dampness, insecticide, the effectiveness of diuretic. Sophora is used insecticide in the clinical treatment of dysentery, hepatitis, urticaria, eczema, bronchitis, etc.. Pharmacological experiments show that matrine alkaloids have ant