Faerie Longbitong capsule of the prostate hyperplasia in experimental animals.docVIP

 PAGE \* MERGEFORMAT 10 Faerie Longbitong capsule of the prostate hyperplasia in experimental animals [Abstract] Objective To observe the Faerie Longbitong capsule model of benign prostatic hyperplasia in experimental animals. Methods for benign prostatic hyperplasia in older dogs and testosterone due to different doses of rat prostate Faerie Longbitong capsule, prostate volume determination in dogs , serum testosterone and estradiol levels. Results older dogs to 5.76,2.88,1.44 g crude drug / kg dose of oral administration, can reduce prostate volume in elderly dogs, but serum testosterone and estradiol levels had no significant effect. Small mice to 28.08,14.04,7.02 g crude drug / kg dose of oral administration of testosterone propionate benign prostatic hyperplasia in mice model has better preventive and therapeutic effects. Conclusion Faerie Longbitong capsule has a good inhibition The role of animal prostatic hyperplasia. [Keywords:] Faerie Longbitong capsule; benign prostatic hyperplasia BPH is a Chinese medicine “Dysuria” category, for the common elderly men, the incidence and cause great suffering to patients. The research group studies based on Chinese medicine theory, developed Faerie Longbitong capsule , intended for the treatment of benign prostatic hyperplasia, this study is to conduct clinical drug research before the pharmacological effects. 1 Materials and methods 1.1 Materials 1.1.1 Drugs: Faerie Longbitong capsule (from Epimedium, psoralen, Salvia, Andrographis, flat storage and other flavors of Chinese medicine composed of Each capsule containing crude drug 1.80 g), 4.76 g crude drug / g powder, from Jilin Pharmaceutical Technology Co., Ltd. to provide day, batch number: experiment capsules, the powder is not taken to the concentration of liquid water, dubbed required. positive control: Longbitong capsule, powder content of 0.3 g / grain (this drug-free crude drug labeling experiments in the dosage amount for the po