Flat stomach ulcer effect of extract of anti-ulcer.docVIP

 PAGE \* MERGEFORMAT 10 Flat stomach ulcer effect of extract of anti-ulcer [Abstract] Objective To observe the level of gastric ulcer gastric ulcer model extract of three kinds of protective effect of the treatment of animals, and to explore mechanisms. Methods The animals were divided into saline control group (negative control) and the stomach Su granule group (positive control), stomach ulcers flat small, medium and large dose group five groups, each gavage for some time, according to the traditional method of making model-induced gastric ulcer formation, then calculate the ulcer area; determination of gastric volume, gastric acidity, pepsin activity and comparative analysis with the control group. The results of gastric ulcer-ping extract can inhibit the pyloric ligation ulcer in rats, mice reserpine ulcer formation; the promotion of acetic acid ulcer of the more burning platform; inhibit gastric secretion, reduce gastric acidity and pepsin content of . In addition, the drug on gastrointestinal motility in mice has a strong role in promoting; can inhibit the acetic acid writhing response in mice. Conclusion flat stomach ulcer extract on various types of gastric ulcer have different levels of preventive and therapeutic effects, its mechanism may be related to the drug can reduce the ulcer rat gastric acid secretion. [Keywords:] stomach ulcer-ping; gastric ulcer; rats; preventive effect Abstract: ObjectiveTo investigate the preventive and therapeutic effects of Weiyangping Extract (WYPE) on gastric ulcer of rats and mice induced by different methods, and to exploit its possible mechanism. MethodsDrugs were administrated, and then the models of gastric ulcer were established according to traditional methods. The area of ulcer was calculated and the contents of gastric juice, pepsin and the gastric acidity were measured.ResultsWYPE could not only inhibit the formation of gastric ulcer of rats induced by pylorus ligature and of mice induced by reserpine, but