Fluid levels of MCP-1 correlation with systemic lupus erythematosus.docVIP

 PAGE \* MERGEFORMAT 15 Fluid levels of MCP-1 correlation with systemic lupus erythematosus [Abstract] Objective: To investigate the Yunnan Han systemic lupus erythematosus (SLE serum and urine of monocyte chemoattractant protein 1 (MCP-1 levels correlated with disease. Methods: SLE patients serum and urine levels of MCP-1 both enzyme-linked immunosorbent assay (ELISA detection, and methods of using statistical relationship between with SLE. Results: 25 cases of SLE patients in Yunnan Han general, without renal damage and renal damage in SLE serum and urine MCP-1 were significantly higher than the healthy control group (P lt;0.01.SLE group of patients with renal failure urine MCP-1 levels were significantly higher than that of SLE patients without renal failure group, SLE without renal damage with renal failure group and the SLE serum MCP-1 level was no significant difference (Pgt; 0.05.SLE after 2 weeks of treatment in patients with serum MCP-1 levels decreased significantly, although the urine levels of MCP-1 also decreased compared with that before treatment but no significant difference (Pgt; 0.05.SLE serum and urine levels of MCP-1 MCP-1 levels were positively correlated with the SLE DAI score, 24-hour urinary protein, oral ulcers, pleuritis was positively correlated with hemoglobin was between negative correlation. SLE patients with urinary MCP-1 levels and 24-hour urinary protein, pleurisy was positively correlated with complement C3, a negative correlation between hemoglobin. Conclusion: The detection of SLE serum and urine MCP-1 levels help to understand disease activity, and the detection of SLE patients with urine levels of MCP-1 will help understand the extent of kidney damage in patients. SLE patients with renal damage recovery slower. [Keywords:] systemic lupus erythematosus, lupus nephritis, monocyte chemoattractant protein-1 Abstract Objective: To analyze the relevance between the MCP-1 levels and its pathological changes in the blood s