Four excellent combination Dioscorea collettii Shenshi Tang on acute gouty arthritis of IL1 PGE2 Experimental Study of the impact of.docVIP

 PAGE \* MERGEFORMAT 12 Four excellent combination Dioscorea collettii Shenshi Tang on acute gouty arthritis of IL1 PGE2 Experimental Study of the impact of Of: Yehong Fang Huang Ping Shou Qi Yang Zhong Ying-Hua [Abstract] [Objective] The excellent combination of four Dioscorea collettii Shenshi Treatment of Acute Gouty Arthritis Study the role. [Methods] injection to the rat ankle joint solution of sodium urate of acute gouty arthritis model, the four excellent combination Dioscorea collettii Shenshi soup for the model treatment, and control groups with colchicine did observe the degree of joint swelling, joint local IL 1, PGE2 in rats. [Results] 1. Large Rat ankle swelling: After modeling 4h, high dose group, middle dose Medicines swelling decreased (P lt;0.05); after the model 12h, high dose group, middle dose Medicines swelling was significantly reduced ( P lt;0.01), low-dose medicine group differences (P lt;0.05); after the model 24h, high dose group, middle dose group were significantly different from traditional Chinese medicine (P lt;0.01); after the model 48h, high dose group there are differences (P lt;0.05), the dose of traditional Chinese medicine group differences (P lt;0.05); 2.IL 1: joint group of local high dose IL 1 decreased (P lt;0.05); 3.PGE2: joint local high dose group PGE2 decreased (P lt;0.05). [Conclusion] Shenshi Dioscorea collettii together four wonderful soup can reduce the crystallization of sodium urate in acute gout arthritis caused by swelling, reduce joint local IL 1, PGE2 levels. [Keywords:] Four excellent combination Dioscorea collettii Shenshi soup; gout; arthritis Abstract: [Objective] To confirm the role of simiao bixie decoction for dying dampness in the treatment of experimental acute gouty arthritis. [Methods] Use the treatment of simiao bixie decoction for dying dampness to the model established by injecting monosodium urate (MSU) solution into ankle cavities of the rats, and compare with colchicine, to obse