Guizhi Decoction on the semi-bionic extraction method preferred combination medicine_0.docVIP

 PAGE \* MERGEFORMAT 14 Guizhi Decoction on the semi-bionic extraction method preferred combination medicine [Abstract] Objective To optimize the extraction and Guizhi Decoction when the best combination medicine. Methods fried herbs mixed into groups and cassia twig, licorice single fried mixed group, with the semi-bionic extraction method, as glycyrrhetinic acid extract , cinnamic acid, flavonoids, volatile oils, the determination of dry extract and 50% ethanol solution of the HPLC fingerprint of refined comparison. Results Except for dry extract content of 2 similar combination of extracts, the other four indicators decoction mixed ingredients were significantly higher than fried mixture, 2 of extract combinations no significant difference in HPLC fingerprints, HPLC gradient elution characteristics of the total integration area and the main peak area: mixed decoctiongt; Single-fried mixture. Conclusion Guizhi soup Recipe ingredients from time to better Guizhi fried mixed with licorice. [Keywords:] Guizhi soup, half-bionic extraction, glycyrrhetinic acid, cinnamic acid, flavonoids, volatile oil, fingerprints Abstract: Objective To optimize the best ingredients combination of Guizhi Gancao Decoction. Method The prescription was put into two groups, and extracting by semi-bionic extraction. The contents of Glycyrrhetinic acid, Cinnamic acid, total flavones, volatile oil and dry extract in the each extract were determined, and HPLC fingerprint of the refined by 50% ethanol was compared. Results Except the similar content of dry extract in two kinds of combinations, the other four index components in mixed extract is significantly higher than individual extraction. Two kinds of combinations extract fingerprints of the HPLC had no significant difference. HPLC gradients eluting total score area and main characteristic peak area in mixed extract were higher than individual extraction. Conclusion It is better that Guizhi Gancao Decoction extracted with Guizh