Hanning analysis of animal model of blood stasis Review.docVIP

 PAGE \* MERGEFORMAT 17 Hanning analysis of animal model of blood stasis Review Keywords:] cold coagulation Blood, animal model, review Hanning blood stasis is a common clinical syndromes, one of ancient Chinese literature Hanning has more discussion of stasis, including “lt;Su asked menstruation ongt;gt; said:” The blood who thermophilic and evil cold, cold is weeping (Shibuya) but no, temperature is the elimination away. “lt;lt;to treat patients on thegt;gt; said:” The cold is the blood knot, warm the blood elimination. “lt;lt;Medical Lin Correctiongt;gt; also says: “you catch cold blood clots.” all that cold lead to an important cause of blood stasis. cold and the main income for the Yin Xie cited, their sexual stagnate, whether cold or the cold outside, can cause blood does not run Chang, the formation of blood stasis, block Xinmaitong. all kinds of heart disease, especially coronary heart disease, pulmonary heart disease, high incidence of winter, usually caused by Haner recurrence increased. Experimental study of cold coagulation blood stasis is stasis of a relatively weak link. Hanning blood stasis animal model is an important platform to carry out the study, but there is no ideal animal model for cold coagulation of blood stasis. Now nearly 10 years of cold coagulation of blood stasis animal model profiles are reviewed, to provide ideas for further research and methods. A partial freezing method Wu et al [1] According to blood stasis and systemic or local blood circulation disorders of the principle, the use of frozen rabbit hind legs, causing blood stasis animal model of cold coagulation. Method: cut the net on both sides of hind foot rabbit hair, with 70% alcohol disinfection, up, down, left, right around home ice (3 copies of the ice crystals were calcium chloride +1, crushing mixing, the temperature dropped to minus 20 ~ 25 ℃). frozen 1.5 h, at 45 ℃ rewarming in warm water 5 min (room temperature 12 ℃). OUTCOME MEASURES: measuring re