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Helicobacter pylori and gastroduodenal diseases
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Helicobacter pylori and gastroduodenal diseases
Many studies indicate that Helicobacter pylori (HP) is a major cause of chronic gastritis, peptic ulcer may also be one of the major risk factors, on the other hand, chronic gastritis and gastric cancer are closely related, both in terms of epidemiology, pathology, immunity, biochemistry, etc. There are many similarities. atrophic gastric mucosa of chronic gastritis intestinal metaplasia dysplasia cancer model this process has been endorsed by many domestic and foreign instructors. So the treatment for HP infection, many scholars made a number of measures, and recommend the eradication of HP’s “triple three weeks” program. to the treatment of gastrointestinal diseases there is a new prospect.
1 HP and chronic gastritis Hp non-autoimmune chronic gastritis, especially the roots of chronic active gastritis Law who has reached the required KOCH. HP settled in the bottom of mucus, thick mucus like jelly, can effectively block access to the stomach cavity components and HP, HP’s Urease breaks down urea that is surrounded by a layer of “ammonia cloud” around the same time, HP generated by H + HCO3-. The two mechanisms that form around HP hypoxia, caused by weak acid survival benefit HP and propagation of micro environment. chronic active gastritis, HP infection rates often above 80%. in our hospital from 1991 to 1993, chronic active gastritis and urease test and measurement applications, tissue sections Warthin starry silver stain detection of bacteria, HP detection rate of 83%, with domestic and foreign reported the same, and for HP treatment of the gastritis symptoms, pathological changes significantly improved.
2 HP and peptic ulcer (PU) Data suggest that a large number of studies, PU, #8203;#8203;especially duodenal ulcer (DU), HP is one of the major risk factor, however, the relationship between HP and the PU is not a specific, non-ulcer dyspepsia, even in asymptoma
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