High-sensitivity C-reactive protein and cerebral hemorrhage.docVIP

 PAGE \* MERGEFORMAT 14 High-sensitivity C-reactive protein and cerebral hemorrhage Of: Wangquan Lan Wu Yuchen Li Xiaobing [Key Words] high-sensitivity C-reactive protein, brain hemorrhage Refers to non-traumatic cerebral hemorrhage within the brain parenchyma of spontaneous bleeding, accounting for about 10% of stroke by 30%. Some studies show that cerebral hemorrhage bleeding site and surrounding tissue inflammatory reaction exists, is secondary to cerebral hemorrhage pathophysiology of brain damage an important part of (1). high sensitivity C-reactive protein (hs CRP) is the most valuable of acute phase protein, which can increase inflammation in the incident prompted, hs CRP is inflammation, infection, tissue damage, necrosis, and an important sign of malignancy (2). studies suggest that hs CRP in the 3 mg / L or more, heart, brain and high risk of vascular events, which in coronary heart disease, stroke, peripheral vascular embolism disease diagnosis and prediction play an increasingly important role, even considered to be the heart, stroke risk assessment of the gold standard (3.) tissue damage after cerebral hemorrhage and edema and inflammatory response, hs CRP can be used as disease level prognostic sign. Biochemical properties of 1 hs CRP 1.1 hs CRP synthesis and release of hs CRP in infection, inflammation or tissue damage by the inflammatory lymphokines interleukin-6, interleukin 1, tumor necrosis factor stimulate the synthesis of liver epithelial cells. The latest research shows that the kidneys are two organs can secrete hs CRP ( 4). In addition, vascular endothelial cells and alveolar macrophages can also induce expression of hs CRP. in physiological conditions, the body of hs CRP synthesis at low rates to the higher affinity with the endoplasmic reticulum connected to, acute inflammation, hs CRP in interleukin 6 and other cytokines induced the expression of the rapid increase, the endoplasmic reticulum junction hs CRP conformat