Hong Thai side of the diarrhea-predominant irritable bowel syndrome colon1 heme oxygenase and nitric oxide synthase mRNA expression.docVIP

 PAGE \* MERGEFORMAT 16 Hong Thai side of the diarrhea-predominant irritable bowel syndrome colon1 heme oxygenase and nitric oxide synthase mRNA expression Of: the Feng Yan, Tao Shuangyou, Luo Qi, Zhou Fusheng, Liao Rongxin [Abstract] [Objective] To soothe the nerves and Stomach Shuganjianpi Hong Thai side of the composition of liver depression and spleen diarrhea-predominant irritable bowel syndrome (D IBS) colonic mucosa of patients with heme oxygenase (HO 1) and nitric oxide synthase (iNOS) mRNA expression. [Method] 63 patients treated subjects were randomly divided into 2 groups and control groups. Treatment of 32 cases of oral treatment with Hong Thai side, the control group had 31 cases of oral treatment Schutt , group 2 a course of 8 weeks. another with 15 healthy subjects as control group. symptom scores before and after treatment to improve the situation and colon mucosa HO 1 and iNOS mRNA expression changes. [Results] (1) treatment group The symptom score decreased significantly compared with before treatment (P lt;0 05), except the control group after treatment of abdominal pain, bloating, loose stools and other symptom scores decreased significantly compared with before treatment (P lt;0 05), the other symptom scores before and after treatment the difference was not significant (Pgt; 0 05). (2) After treatment, group 2 HO 1 the average optical density values were significantly lower, iNOS protein was unit were significantly higher (compared with before treatment, P lt;0 05 or P lt;0 01). the treatment group after treatment compared with the control group, there was no significant difference (Pgt; 0 05), prompt treatment group had recovered to the level of the normal control group; and control group after treatment compared with the control group, the difference was significant (P lt;0 05), prompted not yet recovered to the normal control group, the control group. (3) After treatment, group 2 colon relative expression of iNOS gene were s