Imaging in the assessment of neoadjuvant chemotherapy for osteosarcoma of the significance of.docVIP

 PAGE \* MERGEFORMAT 19 Imaging in the assessment of neoadjuvant chemotherapy for osteosarcoma of the significance of Of: Liu Jian, Guo Wei, Yang Rongli, Qu Hua Yi, Yang Yi [Keywords:] Osteosarcoma Osteosarcoma is the most common primary malignant bone tumor, primary malignant tumor of bone accounts for about 20%, 80% of the patients already at diagnosis of small pulmonary metastases. Osteosarcoma previously treated with surgery as the main method The 5-year survival rate of 20% .20 In the 70 years since the high-dose chemotherapy used in the treatment of osteosarcoma, the osteosarcoma of the 5-year survival rate was significantly improved. now the standard treatment for osteosarcoma model: preoperative chemotherapy + surgery plus chemotherapy combination of integrated treatment model. makes the introduction of chemotherapy in patients with osteosarcoma of the 5-year survival rate of 70% to 80%. At the same time as the application of preoperative chemotherapy, the patients with limb salvage rate of 80% or more, and its 5-year survival and 5-year disease-free survival of patients with amputation were no significant differences. other than the effects of chemotherapy into surgery a key factor in the prognosis of osteosarcoma. Therefore evaluation of osteosarcoma chemotherapy has become the focus of research in recent years. preoperative assessment of the effects of chemotherapy, would constitute a complete new concept of adjuvant chemotherapy. including: clinical assessment, radiographic evaluation and histopathological evaluation of 3. This article reviews the radiographic evaluation only. 1 X-ray film X-ray diagnosis of osteosarcoma in the process of significant value has no substitute. In assessing response to chemotherapy, the tumor volume is reduced, soft tissue calcification in the residual tumor, medullary cavity and periosteal reaction became clear was that the border is good prognostic factors. On the contrary, soft tissue mass unchanged o