Immunohistochemistry in pulmonary neuroendocrine tumor pathological diagnosis_0.docVIP

 PAGE \* MERGEFORMAT 9 Immunohistochemistry in pulmonary neuroendocrine tumor pathological diagnosis Of: Lee, Deng Zhiyong, Song, Chen Jinzhen, Zhang Yang [Abstract] Objective To investigate the clinical features of neuroendocrine carcinoma of the lung and immune pathological type. Methods in our hospital 14 cases of neuroendocrine carcinoma of the lung pathology and clinical data were analyzed. Results neuroendocrine carcinoma of the lung cancer detected in the same period accounted for 12% ( 14/117, 10 cases were male, accounting for 71.4% (10/14. neuroendocrine carcinoma of the immune markers NSE Syn CgA positive rate was 92.9%, 71.4%, 64.3%. Conclusion neuroendocrine carcinoma of the lung with a high degree of malignancy, rapid development , accompanied by early local or distant metastasis. there is such a number of epithelial and neuroendocrine differentiation, combined a number of immune markers can greatly improve the detection rate of pulmonary neuroendocrine tumors. [Keywords:] lung cancer, neuroendocrine, immunohistochemistry, prognosis The latest version of the current WHO classification of the pulmonary neuroendocrine lung cancer is divided into carcinoid, atypical carcinoid, small cell carcinoma and large cell neuroendocrine carcinoma, of which small cell lung cancer (SCLC) accounts for 15% of all lung cancer 20% . Compared with non-small cell lung cancer, although there are indications of the incidence of SCLC seems to have a steady downward trend, but because of the unique biological behavior of tumor types, with non-small cell carcinoma of the difference between the treatment and prognosis, so the incidence of SCLC , diagnosis and treatment of lung cancer in the whole still a considerable proportion. In order to understand neuroendocrine carcinoma of the lung clinical and pathological features and immunological phenotype of immunohistochemistry in the pathological diagnosis of value to me now Institute of Pathology, by light microsco