Infusion of iron ions on the preparation of clarity.docVIP

 PAGE \* MERGEFORMAT 9 Infusion of iron ions on the preparation of clarity [Keywords:] clarity iron infusion preparations Preparation unit a few years ago I had metronidazole injection, sodium chloride injection and other infusion products clarity exists the phenomenon of failed batch, the microporous membrane sediments collected after the test analysis, the main component was iron-like reaction.’s current domestic production of large infusion of equipment used primarily for stainless steel pipe, and made of stainless steel due to the production process, surface polishing, high temperature and pressure, and acid, alkali, salt is not absolute does not affect the removal of iron rust [1], it is necessary infusion of iron ions on the impact of agents in order to improve the quality of preparation of the stability of the infusion. experimental methods and results 1. Instruments and Materials SPM 10B pH meter (standard factory equipment Lai Shan, YB type clarity detector (Tianjin Optical Instrument Factory, TG308 (A) type analytical balance (Gordon Instrument Instrument balance. (2) material Sodium chloride (for injection, Hebei, Shanghai Hua pharmaceutical, batch number: 0031002, metronidazole (for injection, chemical medicine Hechi, batch number: 0030816, Ciprofloxacin (injection, the new system in Zhejiang Xinchang in Beijing drug, batch number: 0040102, glucose (injection, Chongqing Daxin Pharmaceutical Co., batch number: 0040728, needle with activated carbon (medicinal, timber plant carbon factory in Hangzhou, batch number: 0040213,0.187 mg / mL of iron solution ( self-made, batch number: 0080225,0.05 mol / L EDTA 2Na solution (self-made, batch number: 0080225,10% hydrochloric acid (self-made, batch number: 0080225, ammonium thiocyanate solution (self-made, batch number: 0080225 . 2. Methods and Results (1) turbidity, sediment of the identification test membrane preparations retain the identification of sediment: Choose a pharma