Intrahepatic cholestasis of pregnancy on early intervention on the prognosis of perinatal children.docVIP

 PAGE \* MERGEFORMAT 9 Intrahepatic cholestasis of pregnancy on early intervention on the prognosis of perinatal children [Keywords:] intrahepatic cholestasis of pregnancy early intervention child perinatal outcome Intrahepatic cholestasis of pregnancy (intrahepatic cholestasis of pregnancy, ICP) is a unique third trimester to the skin characterized by itching and cholestasis, a greater threat to the fetus is one of the high-risk pregnancy, so that perinatal morbidity and mortality in children rate increased. Although many scholars to the cause, placental pathology, diagnosis and treatment, and many other studies, it is still a lack of effective control measures. now the final treatment of our hospital were retrospectively 92 patients with ICP analysis, to early intervention improve the prognosis of perinatal children. Subjects and methods 1. Target: January 2004 to January 2007 ICP Yuxi City Hospital, 92 patients hospital delivery, the total number of hospital deliveries over the same period was 7 252 cases, ICP incidence rate was 1.27% (92 / 7, 252) .72 cases of our hospital for check- patients when the diagnosis of ICP .20 for the early intervention group patients without hospital for check-in, but in the hospital giving birth, a diagnosis of ICP patients untreated patients without the intervention group .2 In general, the difference was not significant ( Pgt; 0.05), see Table 1. Table 12 Comparison of general patients 2. Diagnostic methods and criteria: 2 groups of pregnant women admitted to hospital treatment or pumping 8:00 to 10:00 the next morning fasting serum total bile acid checks (TBA), alanine aminotransferase (ALT), aspartate amino- aminotransferase (AST), total bilirubin (TBIL), direct bilirubin (DBIL), indirect bilirubin (IBIL). (1) ICP diagnostic criteria. pruritus during pregnancy appears to mainly the main symptoms; abnormal liver function, serum ALT or AST was mainly mild to moderate increase, about up to 60 ~ 100 U, 200 U or