Intravenous fentanyl and lidocaine inhibit the cough response induced by the clinical observation.docVIP

 PAGE \* MERGEFORMAT 9 Intravenous fentanyl and lidocaine inhibit the cough response induced by the clinical observation [Abstract] Objective To observe the pre-injection of intravenous lidocaine during general anesthesia induced cough response induced by different doses of the inhibitory effect of fentanyl. Methods 120 patients required general anesthesia for elective surgery were randomly divided into lidocaine group ( Lidocaine 1.5mg/kg fentanyl 3g/kg, group (lidocaine 1.5 mg / kg fentanyl 5g/kg and the control group (normal saline 5ml fentanyl 3g/kg, group (saline 5 ml fentanyl 5g/kg, observed after the injection of 4 fentanyl incidence and degree of coughing. Results In the control group and group patients with cough rates were 53.33% and 66.67%, Li Duoka because of , group pre-injection of intravenous lidocaine 1.5 mg / kg, the fentanyl-induced cough rates were reduced to 20% and 26.67%, significantly lower than the control group , , no cough difference between the two groups highly significant (P all lt;0.01. Conclusion Intravenous lidocaine pre-induction period can effectively reduce the incidence of cough caused by fentanyl. [Keywords:] anesthetic, lidocaine, fentanyl, cough Fentanyl during the induction of general anesthesia is commonly used drugs, in addition to achieve satisfactory analgesia, but also can effectively reduce the induced and the stress response during tracheal intubation, intravenous fentanyl but often occurs in patients after intense cough response, resulting in intracranial pressure, intraocular pressure, intra-abdominal pressure and blood pressure increased rapidly, the intracranial pressure, open trauma, hydatid disease, and aneurysms can cause serious complications, even life-threatening [1 ]. As often lidocaine can effectively prevent and reduce intubation and bronchoscopy in the cause of the cough response, our department intends to advance a small dose of intravenous lidocaine, the effects of lidocaine on cough