Latanoprost 0.005% eye drops reduce intraocular pressure alternative.docVIP

 PAGE \* MERGEFORMAT 9 Latanoprost 0.005% eye drops reduce intraocular pressure alternative [Abstract] Objective: To evaluate the 0.005% latanoprost eye drops on the application of timolol eye drops 0.5% in poorly controlled intraocular pressure in primary open-angle glaucoma patient outcomes and safety. Methods: 0.5 % timolol eye drops in a single drug with poorly controlled intraocular pressure in primary open-angle glaucoma 40 patients given latanoprost 0.005% eye drops replacement therapy. some medicine for 1 night, 1 drop each time. consecutive points 4,8,12 weeks after treatment of intraocular pressure were compared with the baseline IOP, and blood pressure, heart rate and other systemic and local adverse reactions. Results: The baseline intraocular pressure of patients in this study was (23.7 +-3.3mmHg consecutive points 4,8,12 weeks after intraocular pressure drugs were (17.6 +-2.4mmHg, (17.7 +-1.9mmHg, (17.7 +-2.5mmHg, after treatment, IOP was lower than the baseline IOP (P lt;0.05 . 4,8,12 weeks after treatment effect of lowering intraocular pressure, the difference was not significant. before and after treatment, visual acuity, visual field, heart rate, blood pressure and no significant change. The main adverse events were conjunctival congestion, but without prejudice to continued drug use. Conclusions: 0.005% latanoprost eye drops 0.5% in the treatment of ocular timolol eye drops with poorly controlled primary open angle glaucoma patients is effective and safe. [Keywords:] Latanoprost intraocular pressure in primary open-angle glaucoma Latanoprost is a prostaglandin derivative, and other types of anti-glaucoma drugs, it has a new mechanism of action, by increasing the uveal scleral outflow of aqueous channels reduce intraocular pressure. A long time, people have found prostate element has a lower intraocular pressure, but the side effects, eye can not be tolerated, and no significant stimulation of latanoprost, and almost no systemic side