Liyan Granules Experimental Study of anti-inflammatory effect.docVIP

 PAGE \* MERGEFORMAT 5 Liyan Granules Experimental Study of anti-inflammatory effect Song Yi 1, Wang Wei 2, Wang Shi 1, Zhang Xin 1, Yong-Lin Liu 1, Li-kang granule by an enlightened Liyan Yu-chu, puerarin, Anemarrhena, Ophiopogon japonicus and other traditional Chinese medicine composed by clinical observation of acute and chronic pharyngitis and tonsillitis there is a certain effect, with heat-clearing and detoxifying, anti-inflammatory pain, the efficacy of Qi phlegm. Now its anti-inflammatory effect of acute and chronic experimental studies are as follows. An experimental material 1.1 Drugs Liyan Granules (non-concentrated liquid additives containing health dose 2894.7g / L), provided by China Medical University (990,715); throat Ji Ling Capsule (981,004) from Tianjin Pharmaceutical Co., Ltd. Meilen production; A Division Aspirin (990,418) from Shenyang Medical College production; according to the text Silan (941,117), 5 - hydroxytryptamine (65-02-28) Fluka imported packaging and Shanghai Chemical Reagent-packing plant procurement and supply station. 1.2 animals, Wistar rats, from the Experimental Animal Center of China Medical University, Animal Production Qualified Certificate No.: Liaoning real All the words of Article 1, the quality level, qualified Certificate No.: No. 008 Liaoning real characters from the Laboratory Animal Management Committee of Liaoning Province issue. 2 Methods and Results [1 ~ 3] 2.1 The role of inhibiting capillary permeability in rats taking 60, weighing 200 ~ 250g, male and female in half, 10 in each group. Were randomly divided into 6 groups, granules Ⅰ , Ⅱ , Ⅲ respectively to the granules 104.0g/kg, 52.0g/kg, 13.0g/kg (the amount of liquid contained in the crude drug), saline control group was given normal saline 20ml/kg , aspirin group was given aspirin 268mg/kg, throat disease group to the throat Ji Ling Ling 268mg/kg, each group was administered ig or saline 30min after the rats back left side of the cente