Methotrexate treatment of juvenile rheumatoid arthritis and nursing observation of 35 cases.doc

 PAGE \* MERGEFORMAT 8 Methotrexate treatment of juvenile rheumatoid arthritis and nursing observation of 35 cases [Abstract] Objective To observe the low-dose methotrexate treatment of juvenile rheumatoid arthritis treatment and treatment related to nursing period. Methods to methotrexate (MTX0.25 ~ 0.8mg / (kg times a week, an intravenous input, daily for 8 to 12 weeks. Results of 27 cases remission, accounting for 77.14%, 3 patients died, 5 patients with disabilities. Conclusion Low dose methotrexate for the treatment of children with juvenile rheumatoid arthritis with good results, in earnest observation and take care Under the nursing intervention, MTX treatment of juvenile rheumatoid arthritis is safe. [Keywords:] juvenile rheumatoid arthritis, methotrexate Care Period of juvenile rheumatoid arthritis is a common connective tissue disease in children, its main characteristics with chronic arthritis, and accompanied by systemic involvement, including the joints, muscles, liver and spleen and lymph nodes. For the effective treatment of juvenile rheumatoid arthritis, reduce relapse, reduce disability, our department under the condition in the general wards with a small dose of methotrexate treatment of juvenile rheumatoid arthritis in 35 cases, children with the disease have eased, and through the MTX side effects during treatment and close observation care, and achieved good results. 1 Clinical data 1.1 General Information The group of 35 patients to our department from January 2005 ~ February 2006 in children with juvenile rheumatoid arthritis admitted to the diagnosis are in line with American College of Rheumatology diagnostic criteria [1]. Male 25, female 10 cases, 3 to 7 years in 5 cases, 30 patients aged 8 to 15, less joints in 13 cases, 12 cases of polyarticular, systemic in 10 cases. 1.2 before treatment, during treatment to check blood, urine, liver and kidney function, these indicators are normal, the treatment for this projec