Muskrat chemical constituents and pharmacological effects of.doc

 PAGE \* MERGEFORMAT 5 Muskrat chemical constituents and pharmacological effects of Author: Liu Ke-feng, Li Zhuo, ZHANG Hui-Yu Yang, LIU Da - [Keywords:] muskrat; chemical composition; pharmacological effects In recent years, natural musk and other animal drugs lack of resources at home and abroad are looking for new resources. Muskrat resources, widely distributed, the number of large, easy feeding, good management, and contains the features and elements similar to musk, has aroused widespread concern in academic circles. 1 Studies on chemical constituents 1.1 The physical and chemical properties through adult muskrat balm, physical and chemical properties of the tests carried out using plasma emission spectrometer determination; other indicators are used for chemical analysis methods, results: acid value (3.70), ester value (1.82), saponification value ( 2.3 ug / g), crude fat (1.6 ug / g), water-soluble material (amp;lt;1.0 ug / g), alcohol-soluble material (amp;lt;0.1 ug / g), ether soluble material (amp;lt;1.0 ug / g). 1.2 Chemical composition [1] the use of color - mass spectrometry techniques, adult muskrat balm extract the various components were identified (mass spectrum omitted), using area normalization method, for each group were analyzed quantitatively, the qualitative and quantitative results are as follows: lauric acid (0.39), 9 - 18 en -1 - ol (0.47), cyclo-15 oxazolidinone (5.53), musk ketone (2.21), 16 methyl ester (9.15), 9 - 16 acid (3.54), palmitic acid (7.20), cyclo-17 oxazolidinone (12.87), civet ketone (3.45), Central City, 12 alcohol (0.79), 9 - 18-ene methyl ester (5.15 ), 8 - 18 acid (0.47), cis -9 - Shap acid (9.90), anti--9 - Shap acid (0.95), cyclo-12-one (0.42), 9,12 - 18 acid, 2 - hydroxy -1 (hydroxymethyl) has ester (0.42). Kim Sun Dan and others through the Muskrat Sachet of benzene extract of unsaponifiable constituents of the thin-layer separation obtained with the standard Rf values of musk ketone the same compositi