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MxA protein and allergic purpura discussion about sex
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MxA protein and allergic purpura discussion about sex
[Abstract] Objective To investigate the MxA protein and allergic purpura (HSP)-related disease. Methods 29 cases of HSP patients and 14 normal children, peripheral blood lymphocytes by flow cytometry MxA protein, ELISA assay of serum IFN | Coxsackie virus B group @ and (CBV-IgM, EB virus (EBV-IgM, adenovirus (ADV-IgM. Results ① HSP group rate of MxA protein was compared with control group the difference was highly statistically significant (P lt;0.01), ② HSP Group IFN | @ positive rate with the control group the difference was statistically significant (P lt;0.05, ③ HSP Group CBV | IgM, EBV | IgM, ADV | IgM positive rate compared with control group the difference was not statistically significant (Pgt; 0.05, ④ HSP Group MxA protein and IFN | @ positive rate was statistically significant difference (P lt;0.05. Conclusion virus allergic purpura may be an important incentive, MxA protein could detect the virus infection as an ideal target.
[Keywords:] allergic purpura MxA protein in viral infections
Henoch-Schonlein purpura (HSP) is a common pediatric systemic vasculitis, can affect the heart, brain, kidneys and other vital organs. In recent years, showing a rising trend in its incidence [1], viral infection might be important causes of morbidity [2] . China mainly through the detection of IFN | α and viral antigens and antibodies to investigate the relationship between allergic purpura. There are found, MxA protein and a closely related virus infection [3]. This paper by examining HSP patients and normal control children lymphocyte MxA protein, serum IFN | @ and the Coxsackie B group viruses (CBV-IgM, EB virus (EBV)-IgM, adenovirus (ADV-IgM to explore their relationship with the pathogenesis of HSP.
1 Materials and Methods
1.1 General Information
HSP 29 cases, as from November 2007 to April 2008 at the First Hospital of Lanzhou University, outpatient and inpatient pe
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