Nasopharyngeal carcinoma after radiotherapy cranial nerve injury research.doc

 PAGE \* MERGEFORMAT 4 Nasopharyngeal carcinoma after radiotherapy cranial nerve injury research [Abstract] radiation cranial nerve injury is patients with nasopharyngeal carcinoma after radiotherapy, one of the more common complications that seriously affect the patient’s quality of life. Article on their incidence, pathogenesis, clinical manifestations, diagnosis, treatment and prevention are reviewed. [Keywords:] nasopharyngeal cancer radiotherapy cranial nerve injury Past majority thought that the peripheral nerve of the radiation than the resistance, lack of knowledge of radioactive nerve injury. With the extension of survival in patients with radiotherapy and the people are demanding higher quality of life, radiation injury of peripheral nerve gradually being attention. It is reported in the literature of nasopharyngeal carcinoma after radiotherapy the incidence of cranial nerve injury in approximately 5% to 20% [1,2], individual reports a far cry from, mainly with the irradiation dose, irradiation technique, the patient survival time and statistical methods related to , radioactive nerve injury can occur in a few years after radiation therapy, or even a few decades, the length of follow-up period will also affect the occurrence rate. According to Kong Lin et al [3] reported that radiation cranial nerve injury in 5-year cumulative incidence rate was 10.3%, 10-year cumulative incidence of 25.4%, the cumulative incidence curve upward trend shows that with the extension of survival time, radioactive cranial The incidence of nerve injury would be increased year by year, such as the follow-up period long enough to underestimate the radiation incidence of cranial nerve injury. A disease mechanism and influence factors Radioactive nerve injury occurred in accordance with its time can be divided into acute injury, early-onset delayed injury and late-onset delayed injury. Early injury mainly for a variety of sensory abnormalities observed changes in the neura