Non-alcoholic fatty liver disease drug therapy research abroad.doc

 PAGE \* MERGEFORMAT 5 Non-alcoholic fatty liver disease drug therapy research abroad [Abstract] Non-alcoholic fatty liver disease (NAFLD) is based primarily on pathophysiology of insulin resistance and oxidative stress, while the ease of insulin resistance, reduce oxidative stress, blood lipid and Hugan key strategies such as the treatment of NAFLD. Clinical trials confirmed that rosiglitazone, metformin, vitamin E and C, and so on atorvastatin treatment can ease the varying degrees of abnormal aminotransferase, fatty degeneration, inflammation and liver fibrosis. Good prospects for some drugs, but the lack of sufficiently strong randomized controlled trials, so there are not any special treatment of a drug recommended NAFLD. [Keywords:] non-alcoholic fatty liver disease; drug therapy: rosiglitazone [Abstract] Principal foundation of pathology and physiology in nonalcoholic fatty liver disease (NAFLD) is insulin resistance and oxidative stress,. And therapy strategy of NAFLD mainly includes: lessening insulin resistance, reducing oxidative stress, lipid-modulating and liver-protecting. Clinical trials confirm different level remission of transaminase disorders, steatosis, inflammation and liver fibrosis with treatment of rosiglitazone, metformin, atorvastatin Vitamins E and C etc.The development of many drugs lacks of adequately powered, randomized, controlled trials, so that it is currently difficult to make evidence-based recommendations on pharmacological treatment in NAFLD. [Keywords:] Nonalcoholic fatty liver disease (NAFLD); Pharmacological treatment; Rosiglitazone With the increased incidence of obesity and diabetes, NAFLD has become the focus of the medical profession. Researchers are constantly looking for the ideal drug treatment of NAFLD, this article will be abroad in recent years, some of drug treatment of fatty liver research information to make a profile. A thiazolidinedione (Thiazolidinediones, TZDs) Thiazolidinedione is a kind of in