Olanzapine and fluoxetine in the prevention of clinical observation of depression after cerebral infarction.docVIP
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Olanzapine and fluoxetine in the prevention of clinical observation of depression after cerebral infarction
PAGE \* MERGEFORMAT 4
Olanzapine and fluoxetine in the prevention of clinical observation of depression after cerebral infarction
[Keywords:] cerebral infarction sequelae, depression, olanzapine, fluoxetine
1 Materials and Methods
1.1 Object
Our hospital from 2007 to 2008 collected 60 cases of cerebral infarction, cerebral infarction confirmed by head CT, where 41 males and 19 females, .45 to 83 years, average 65.87 years old, the 60 patients were 0 to 3 muscle. removing a disturbance of consciousness, aphasia, mental patients.
Randomly divided into treatment group 21 males and 9 females, average age of 64.90 years of age, disease duration (3.5 + -2.3 days. When the control group of 30 patients, 20 males and 10 females. The average age of 67.48 years of age, disease duration (3.1 + - 2.6 days. HAMD score, treatment group (10.75 + -3.65 control group (11.05 +-4.58.SSS score, treatment group (15.01 + -5.91 in the control group (14.98 + -6.05. two groups of age, duration, and no difference in HAMD score .
1.2 Methods
Both groups were given Danhong Injection, puerarin, aspirin, and there is intracranial hypertension were given to dehydration, hypertension, diabetes, coronary heart disease were given appropriate treatment. The treatment group were treated with olanzapine (Eli Lilly Company 6.25mg, qn, 14 days, fluoxetine (Eli Lilly 20mg, qd, 28d. admission, after 4 weeks and SSS HAMD rating scale scores.
2 Results
HAMD scores after treatment, the treatment group 14.52 + -2.43 in the control group (21.04 +-3.12.P lt;0.01, significant difference. SSS score treatment group (10.55 + -6.18 in the control group (14.62 + -8.02, P lt;0.01 . There was a significant difference. treatment group 2 patients after serving fluoxetine mild gastrointestinal reactions, the symptoms persist after taking the drug gradually reduced, without dropping out of the observer.
Links to free paper download
3 Discussion
Post-stroke depression (PSD mechanism
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