On the adverse reactions Enoxacin.docVIP

On the adverse reactions Enoxacin [Keywords:] Enoxacin; adverse reaction; clinical symptoms Enoxacin is the first three-generation quinolone antibiotic, an antiseptic, by acting on bacterial DNA gyrase A-subunit, inhibit DNA synthesis and replication of bacteria caused the death, its antibacterial spectrum, especially for the aerobic Gram - high-negative bacilli antimicrobial activity against penicillin-resistant Neisseria gonorrhoeae, Haemophilus influenzae enzyme production and Mora spp are highly antibacterial activity against Chlamydia trachomatis, Mycoplasma, Legionella has a good anti-microbial effect of Mycobacterium tuberculosis and atypical mycobacteria have antibacterial activity. Therefore, Enoxacin the clinical application of agents is now more widely, adverse reactions often occur, this article summarizes the relevant reports in recent years for clinical reference. An allergic reaction GAO Jin-Juan et al [1] reported cases of a patient female, 24 years old, diagnosed with bronchitis, I Enoxacin Gluconate Injection 0.2 g/100 ml intravenous infusion, 5 min after the patients feel palpitations, chest tightness, needle Department sting, since the eye of a needle from a period of up to 20 cm thrombophlebitis, arm skin and see the red rash. An immediate withdrawal, about 30 min after the patients without chest tightness, palpitations, symptoms relieved thrombophlebitis gradually disappear. Example 2, the patient female, 26 years old, clinical diagnosis of tonsillitis, I penicillin G sodium (skin test negative) 4.8 million U 5% glucose 5 00ml, 1 times / d, and Enoxacin Gluconate Injection 0.2 g / 100 ml, 1 times / d. After intravenous penicillin and continue to bit by bit Enoxacin Gluconate Injection of about 50 ml, the patient felt palpitations, chest tightness, tingling needle Department, starting from the needle up to 20 cm section of thrombophlebitis, arm skin and see the red rash. An immediate withdrawal, about 30 min a