Outside the dry mice trachea lung and skin effects of pathological study.docVIP

 PAGE \* MERGEFORMAT 12 Outside the dry mice trachea lung and skin effects of pathological study Authors: Ding Jianzhong, Zhang six pass, Chen Gang, QIU Xin-Fan, Gong rights, Li Kan, Zhang Yuan Keywords: outside the dry;,, trachea;,,, lung;,,,, skin Abstract: Objective To observe the outer dry right mouse trachea, lung and skin effects. Methods 40 specific pathogen free (SPF) level Kunming mice were randomly divided into 4 groups: normal temperature and moisture group (A group), at room temperature dry group (B group), warm dry group (C group), cool and dry group (D group) 10. On the 7th day after treatment with the first 14 days of routine histopathological examination. Results In the first 14 days, C group, D group tracheal epithelial squamous metaplasia, C group Duocheng sheet trachea cilia defects, while the D group Duocheng foci-like defects; two tracheal mucosa of inflammatory cell infiltration than those of the first seven days of weight, accompanied by tracheal gland serous gland epithelial mucus metaplasia (D group of ≥ 40%, C group ≤ 20%), pulmonary congestion and edema. C group epidermis showed irregular shrinkage, significantly reduced the number of hair balls; C group, D group of foot pad skin of epidermal thickening, hyperplasia of connective tissue with less sweat. Conclusion The results for the dry cause outside the trachea, lungs and trachea to provide histopathological basis for glandular lesions. Keywords: External dry; trachea; lung; skin Abstract: ObjectiveTo investigate the pathological effects on windpipe, lung and skins with Outer-Dry.Methods40 kunming mice (SPF) were divided into four groups, including group A (Normal mice), group B (Normal temperature and OuterDry mice), group C (Warm-Dry mice), group D (CoolDry mice), 10 mice / group.The tests were measured in day 7 and 14.ResultsIn group C and D hyperplasia of epithelium cell and infiltrations of inflammative cell in day 14 that were severe than that of