P53 P16 TGFα EGFR VEGF in bladder transitional cell carcinoma tissues and its significance.docVIP

 PAGE \* MERGEFORMAT 2 P53 P16 TGFα EGFR VEGF in bladder transitional cell carcinoma tissues and its significance [Abstract] Objective To investigate the P53, P16, TGF  α , EGFR, VEGF in bladder transitional cell carcinoma tissues and its significance. Methods Immunohistochemical staining of bladder transitional cell carcinoma of the P53, P16, TGF  α , EGFR, VEGF expression, deletion and biological significance were studied. Results Of the 60 cases of bladder transitional cell carcinoma patients with 68.3% (41/60) TGF  α expression, EGFR positive expression rate of 35% (21/60), VEGF positive expression rate of 50% (30/60), P53 positive expression rate of 38.3% (23/60), P16 positive expression rate of 30% (18/60). Conclusion The positive expression rate of P16 in patients with no significant gender-related, with the tumor grade and stage increased and reduced, P53, P16, TGF  α , EGFR, VEGF expression increased with tumor grade and stage increased The significantly increased, and the co-expression of multiple genes in tandem with the tumor grade and stage was significantly higher at higher. [Keywords:] P53 P16 transforming growth factor (TGF) α epidermal growth factor (EGFR) of vascular endothelial growth factor (VEGF) immunohistochemical staining of bladder cancer The expression and significance of P53, P16, TGF  α , EGFR and VEGF in bladder transitional cell carcinoma ABSTRACT: Objective To explore the expression and significance of P53, P16, transforming growth factor  a (TGF  α ), epidermal growth factor (EGFR) and vascular endothelial growth factor (VEGF) in bladder transitional cell carcinoma (BTCC). Methods Immunohistochemistry method was used to study the expression, deletion and significance of P53, P16, TGF  α , EGFR and VEGF. Results The positive expression rates of P53, P16, TGF  α , EGFR and VEGF in 60 cases of BTCC were 38.3% ( 23/60), 30% (18/60), 68.3% (41/60), 35% (21/60) and 50% (30/60) respectively. Conclusion There was