Patients with chronic obstructive pulmonary disease 8iso prostaglandin F2 and C reactive protein.doc

 PAGE \* MERGEFORMAT 11 Patients with chronic obstructive pulmonary disease 8iso prostaglandin F2 and C reactive protein Study: Su Li Ping Li Qi Zhang Aili Han Shuzhi [Abstract] Objective: Chronic obstructive pulmonary disease (COPD) patients 8 iso prostaglandin F2 @ (8 iso PGF2 @) and serum C-reactive protein (CRP) levels, and to explore the pathogenesis of COPD. Methods: Enzyme 27 cases linked immunosorbent assay in patients with acute exacerbation of COPD and 20 healthy controls 8 iso PGF2 @ plasma and serum CRP levels. Results: COPD patients 8 iso PGF2 @ and serum CRP levels were significantly higher than the normal control group, there was a statistically school differences. Conclusions: COPD patients had elevated levels of inflammation and oxidative stress, and participated in the development and progression of COPD, [Keywords:] pulmonary disease / chronic obstructive; 8-iso prostaglandin F2 @; C reactive protein; oxidative stress; inflammation [ABSTRACT] Objective: To investigat the plasma 8 iso prostaglandin F2 @ (8 iso PGF2 @) and the serum C reactive protein (CRP) levels in patients with chronic obstructive pulmonary disease (COPD), and also explore the pathogenesis of COPD.Methods : ELISA method was used to determine the plasma level of 8 iso PGF2 @ and serum level of CRP in 27 patients with acute exacerbation of COPD and in 20 control subjects. Results: The plasma 8 iso PGF2 @ and serum CRP levels in patients with COPD were higher than that in control subjects (P lt;0.01). Conclusion: Oxidative stress and inflammation were increased in COPD which may be involved in the pathogenesis of COPD. [KEY WORDS] Pulmonary Disease / Chronic Obstructive, 8 iso PGF2 @, C reactive Protein, Oxidative Stress, Inflammation Chronic obstructive pulmonary disease (COPD) is a very high morbidity and mortality of the disease, therefore, a clear etiology and pathogenesis of COPD, to find effective means of prevention has been a continuing concern. Study