Pediatric clinical rational drug use.docVIP

 PAGE \* MERGEFORMAT 5 Pediatric clinical rational drug use [Keywords:] pediatric clinical rational drug use A pediatric clinical study of drug treatment and content of the object Pediatric drug therapy in pediatric primary means of preventing and curing diseases, pediatric medicines, is mainly used for children’s drugs. Pediatric clinical drug treatment, said the object of study should be broadly embryo, fetus, newborns, infants, toddlers, preschool, school-age children to adolescence of children. According to China’s practice in general refers to the age of 0 ~ 14-year-old children. Clinical study of pediatric drug therapy includes drugs on the body (including pathogens) in the role and the role of the body of drugs. Drugs on the body (including pathogens) is mainly manifested in the role of pharmacodynamics and toxicology. Pharmacodynamics refers primarily to the role of drugs on the body’s physiological functions leading to the excitement or inhibition of pathogens by interfering with its metabolism and inhibit its growth and reproduction. But at the same drugs on different tissues and organs can have different roles, and with the dose increase or decrease in physiological function of the excitement and inhibition can also transform into each other (two-way drug effect). A drug on the body of various tissues and organs are not always the same role may be one or a few pairs of the role of the organ which is particularly evident in other tissues and organs was not significant (the choice of drug effect), high selectivity of drugs in general negative response to less good effect, but this is only relative. The role of a drug with only a rare, often in several tissues and organs also play different roles. The role of drugs on the human body, in addition to treatment purpose, there is nothing to do with the treatment or even harmful effects, including side effects and toxic effects, so drugs with a dual nature can be healing, but inappropriate use can also