- 1、本文档共9页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
pRb2-p130 cyclinD1 and MUC1 in esophageal squamous cell carcinoma
PAGE \* MERGEFORMAT 9
pRb2/p130 cyclinD1 and MUC1 in esophageal squamous cell carcinoma
Authors: Han Biao, Zhang Xian-wei, Liu Jian, JIANG Peng
【Abstract】 Objective To investigate pRb2/p130, cyclinD1 and MUC1 in esophageal squamous cell carcinoma and its significance. Methods Immunohistochemical staining of pRb2/p130, cyclinD1 and MUC1 in 16 cases of normal esophageal mucosa and 60 cases of esophageal squamous cell carcinoma of the expression level of analysis of their correlation with clinicopathological correlation between the indicators and their three. The results of esophageal squamous cell carcinoma of pRb2/p130 expression with low histological grade, TNM stage, lymph node metastasis, depth of invasion; cyclinD1 high expression of cancer differentiation, lymph node metastasis; MUC1 expression and lymph node metastasis in the high - Related; Kaplan Meier survival analysis showed that high expression of pRb2/p130 survival rate is higher than the low expression group (P = 0.0032, Log Rank test); Cox proportional hazard model analysis showed that pRb2/p130, lymph node metastasis, cancer organizations, the degree of differentiation is esophageal squamous cell carcinoma of the independent prognostic indicators. Conclusion esophageal squamous cell carcinoma in the presence of low pRb2/p130 expression and the high cyclinD1 and MUC1 expression, promote cell growth and tumor development is the occurrence and development of esophageal cancer in the important event.
Keywords: pRb2/p130 cyclinD1; MUC1 immunohistochemistry; esophageal squamous cell carcinoma
Expression of pRb2/p130, cyclinD1 and MUC1 in Esophageal Squamous Cell Carcinoma
Keywords:: pRb2/p130; cyclinD1; MUC1; Immunohistochemistry; Esophageal squamous cell carcinoma
China is one of the world’s high incidence of esophageal cancer, the patient’s morbidity and mortality is high and the prognosis is poor, a serious threat to people’s physical and mental health. Search for
您可能关注的文档
- Poria peel pachymaran Optimization of the extraction process.doc
- Poria Poria in different areas of comparative analysis of acid content.doc
- Poria bacteria quality standards and inspection procedures.doc
- Poria Poria in different areas of comparative analysis of acid content_0.doc
- Poria Root Liquid Song mycelium and the fermentation of polysaccharide_0.doc
- Poria Poria in different regions Comparison of acid.doc
- Poria of the shake flask fed-batch fermentation and fed-batch fermentation tank liquid fermentation.doc
- Population pharmacokinetics in pediatric clinical pharmacology of.doc
- Poria ultrafine powder and the volatile constituents of ordinary.doc
- Poria Combination of significance in the Prescription Analysis.doc
文档评论(0)